Backup Exec 2012 sp2 Deduplication

HI

I bought 2 Backup Exec 3600 apliances to replace my actual Backup Exec server.  For the first time I will use Deduplication.  One box will be on the main site an the other one to the remote site for replication

I will use tapes for long-term data retention

what are your advice on the frequence of the incremental/differentials and full backups?

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